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Q: Is it really important to follow the instructional label on my vitamins when it directs me to take them with food or on an empty stomach?

A: Yes, it is. The recommendations are usually made based on absorption rates of the vitamins/supplements or GI tolerance. Many vitamins/supplements can interfere with each other if they not supposed to be taken together or with food. Others many need to be taken with food to increase absorption or to reduce risk of upsetting your stomach. So, yes, it is important! Always follow the recommendations of the manufacturer or your Clinical Provider.